Figure 2From: Different Partners, Opposite Outcomes: A New Perspective of the Immunobiology of Indoleamine 2,3-DioxygenaseMultiple alignments of the amino acid sequences of IDOs. Mammalian IDOs (H. sapiens, accession number P14902; M. musculus, P28776; R. norvegicus, Q9ERD9; C. canis, XM_532793) and proto-IDOs (hIDO2, human IDO2, NP_919270; mIDO2, mouse IDO2, NP_666061; G. gallus, XM_424397; D. rerio, BAF45469). The alignments focus on the stretch of amino acids containing the putative ITIM1 and ITIM2 motifs. Conserved residues (black boxes) and conservative replacements (gray boxes) are indicated.Back to article page