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Figure 2 | Molecular Medicine

Figure 2

From: Glaucoma-Induced Degeneration of Retinal Ganglion Cells Prevented by Hypoxic Preconditioning: A Model of Glaucoma Tolerance

Figure 2

Total brn3-positive retinal ganglion cell soma density in peripheral retina as measured in retinal flat mounts from experimental (GL; black bars) and fellow eyes (open bars) obtained from untreated control mice (NT) and mice treated with RHP before intraocular hypertension. Results from both the 3-wk (A) and 10-wk (B, C) cohorts are shown, including those from sham mice (shaded bar) in both groups. Representative photomicrographs of brn3-labeled RGC soma (red) in peripheral retina of untreated and RHP-treated mice subjected to 10 wks of intraocular hypertension are also provided (C). *P < 0.05 versus fellow eye in each group; #P < 0.05 versus glaucomatous eye in NT group; +P < 0.05 versus respective sham. Scale bar in C = 50 µm.

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