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Figure 3 | Molecular Medicine

Figure 3

From: Delayed Administration of Pyroglutamate Helix B Surface Peptide (pHBSP), a Novel Nonerythropoietic Analog of Erythropoietin, Attenuates Acute Kidney Injury

Figure 3

Effect of pHBSP and EPO on the phosphorylation of Ser473 on Akt in the kidney (A), Ser9 on GSK-3β in the kidney (B), Ser1177 on eNOS in the kidney (C), p38 in the kidney (D) after sham operation (Sham, n = 3) or renal ischemia-reperfusion injury (IRI, n = 3; IRI + pHBSP, n = 3 (10 ng/kg pHBSP administered 6 h into reperfusion); and IRI + EPO, n = 3 (1,000 IU/kg EPO administered 4 h into reperfusion). Data are expressed as means ± SEM for n number of observations. P < 0.05 versus IRI. O.D., optical density.

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