From: A CYP26B1 Polymorphism Enhances Retinoic Acid Catabolism and May Aggravate Atherosclerosis
Homozygous for the major allele | Carriers of the minor allele | |||||
---|---|---|---|---|---|---|
n | n | P | ||||
Age (years) | ||||||
Patients | 282 | 53.0 (49.0–57.0) | 90 | 54.0 (48.8–57.0) | 0.45 | |
Controls | 282 | 54.0 (49.8–57.0) | 99 | 54.0 (49.0–57.0) | 0.35 | |
Body mass index (kg/m2) | ||||||
Patients | 281 | 26.8 (24.7–29.6) | 90 | 26.6 (24.3–29.5) | 0.70 | |
Controls | 282 | 25.6 (23.5–27.8) | 98 | 25.7 (24.1–27.5) | 0.79 | |
Current smokers (%) | ||||||
Patients | 282 | 50.7 | 90 | 51.1 | 0.52 | |
Controls | 280 | 24.3 | 98 | 24.5 | 0.53 | |
Serum cholesterol (mmol/L) | ||||||
Patients | 280 | 5.0 (4.2–5.7) | 90 | 5.2 (4.5–5.7) | 0.12 | |
Controls | 282 | 5.4 (4.8–6.1) | 99 | 5.5 (4.7–6.2) | 0.50 | |
Serum low-density | ||||||
lipoprotein (mmol/L) Patients | 272 | 3.2 (2.5–3.9) | 84 | 3.2 (2.6–3.9) | 0.33 | |
Controls | 281 | 3.4 (2.9–4.1) | 98 | 3.7 (3.0–4.3) | 0.18 | |
Serum high-density lipoprotein (mmol/L) | ||||||
Patients | 272 | 1.1 (0.9–1.4) | 84 | 1.1 (0.9–1.4) | 0.36 | |
Controls | 281 | 1.3 (1.1–1.7) | 98 | 1.4 (1.1–1.6) | 0.58 | |
Serum triglycerides (mmol/L) | ||||||
Patients | 280 | 1.6 (1.2–2.2) | 90 | 1.6 (1.2–2.3) | 0.88 | |
Controls | 282 | 1.2 (0.86–1.6) | 99 | 1.2 (0.82–1.5) | 0.86 | |
Blood CRP (mg/L) | ||||||
Patients | 272 | 1.39 (0.72–3.19) | 88 | 2.01 (0.74–4.08) | 0.18 | |
Controls | 275 | 0.93 (0.51–1.78) | 98 | 1.04 (0.56–2.03) | 0.35 |