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Figure 10 | Molecular Medicine

Figure 10

From: Sprouty Is a Negative Regulator of Transforming Growth Factor β-Induced Epithelial-to-Mesenchymal Transition and Cataract

Figure 10

Representative images from postnatal-d-15 (A, B) or neonatal (C-G) Spry1-overexpressing transgenic mice depicting phase-contrast microscopy of a whole transparent lens (A), epifluorescence of an intact lens epithelial wholemount stained with TRITC-conjugated lectin (B), PAS-staining (C) or Hoechst labeling (D) of the anterior lens epithelial monolayer, strongly reactive for E-cadherin (E), but not reactive for pSmad2 (F) or Snail (G). le, lens epithelium. Scale bar, B = 20 µm; C-G = 35 µm.

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