Figure 3

M2 immune response after UUO in WT, TLR2, TLR4 and MyD88 KO animals. Percentage of T CD4⁺ cells expressing IL-4 (A) and IFN-γ (B) in WT, TLR2, TLR4 and MyD88 KO animals 7 d after UUO. IL-4:IFN-γ ratio in TLR2, TLR4, and MyD88 KO mice (C). The ratio of WT mice subjected to UUO was considered 1. Percentage of infiltrating CD11b^high (D) and CD11b^low cells (E) and percentage of CD11b^high cells expressing CCR7(F), CD206(G), IL-10(H), IL-12 (p40) (I) and MIG (J) in WT, TLR2, TLR4 and MyD88 KO animals 7 d after UUO. Dashed line represents WT animals not submitted to UUO. *p < 0.05.