IL-4 and IL-12 BM chimera and renal fibrosis. Pelvis proteinuria:creatininuria ratio (A) in WT, KO nonchimeric and in KO chimeric animals. Collagen deposition quantification and staining (B and C) in chimeric animals. Dashed line represents WT animals not submitted to UUO. *p < 0.05, **p< 0.01. Scale bar, 100 µm.