Figure 7

Macrophages influence renal fibrosis development. Pelvis proteinuria:creatininuria ratio (A) in macrophage-depleted WT, Rag-1 KO and WT animals submitted to UUO. Collagen deposition quantification and staining (B and C) in macrophage-depleted WT, Rag-1 KO and WT animals submitted to UUO. Dashed line represents WT animals not submitted to UUO. *p < 0.05. MØ, macrophages. Scale bar, 100 µm.