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Figure 6 | Molecular Medicine

Figure 6

From: Augmenter of Liver Regeneration (ALR) Is a Novel Biomarker of Hepatocellular Stress/Inflammation: In Vitro, In Vivo and In Silico Studies

Figure 6

Concentration-dependent effects of TNF-α and actinomycin D on ALR secretion, DNA synthesis and viability of hepatocytes. Cultured hepatocytes were challenged with indicated concentrations of TNF-α or actinomycin D. The media were aspirated at 24 h for measurement of ALR release (left panels), and DNA synthesis (middle panels) and viability (right panels) of the cells were measured. Results shown are means of triplicate determinations ± SEM from a representative of three separate experiments. *p < 0.05 versus 0; **p < 0.01 versus 0; ***p < 0.001 versus 0.

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