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Figure 8 | Molecular Medicine

Figure 8

From: Augmenter of Liver Regeneration (ALR) Is a Novel Biomarker of Hepatocellular Stress/Inflammation: In Vitro, In Vivo and In Silico Studies

Figure 8

LPS augments actinomycin D-induced release of ALR additively and promotes loss of viability of hepatocytes. Cultured hepatocytes were challenged with 100 ng/mL LPS and/or 10 ng/mL actinomycin D (Act-D). The media were aspirated at 24 h for ALR (A) and LDH (B) measurements, and cell viability was determined via MTT assay (C). Results shown are means of triplicate determinations ± SEM from a representative of three separate experiments. *p < 0.05 versus control; **p < 0.01 versus control; ***p < 0.001 versus control; ¶p < 0.05 versus Act-D.

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