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Table 2 Primary screen reveals unaltered behavioral variables in sepsis-surviving mice.a

From: HMGB1 Mediates Cognitive Impairment in Sepsis Survivors

No

Variable

Scale range

Sham (n = 20)

CLP (n = 20)

Chi-square

d.f.

P

1

Coat length

0ā€“4

0 (0/0)

0 (0/0)

0

1

1

2

Hair length

0ā€“3

0 (0/0)

0 (0/0)

0

1

1

3

Hair morphology

0ā€“2

0 (0/0)

0 (0/0)

1.03

1

0.3112

4

Body position

0ā€“8

5 (3/5)

5 (3/5)

3.24

1

0.0717

5

Spontaneous activity

0ā€“8

3 (3/5)

5 (3/5)

2.56

1

0.1097

6

Respiratory rate

0ā€“3

2 (2/2)

2 (2/2)

0

1

1

7

Tremor

0ā€“2

0 (0/0)

0 (0/0)

0

1

1

8

Defecation

0ā€“13

4 (2/7.5)

4(2/5.5)

0.42

1

0.5186

9

Urination

0ā€“1

0 (0/0)

0(0/1)

0.53

1

0.4652

10

Transfer arousal

0ā€“6

5 (4/5)

5 (4/5)

0

1

1

11

Latency to move

0ā€“10

2 (1/2.5)

2 (1/3)

0.13

1

0.7233

12

Locomotion in arena

0ā€“26

11 (7/14.5)

10.5 (9/12.75)

0.42

1

0.5186

13

Piloerection

0ā€“1

0 (0/0)

0 (0/0)

0

1

1

14

Palpebral closure

0ā€“2

0 (0/0)

0 (0/0)

0

1

1

15

Startle response

0ā€“3

1 (1/1)

1 (1/1)

0

1

1

16

Gait

0ā€“3

0 (0/0)

0 (0/0)

0

1

1

17

Pelvic elevation

0ā€“3

2 (2/2)

2(2/2)

0

1

1

18

Tail elevation

0ā€“2

1 (1/1)

1 (1/1)

1.03

1

0.3112

19

Touch escape

0ā€“3

1 (0/2)

1 (0/2)

0.11

1

0.7357

20

Positional passivity

0ā€“4

1.5 (0/4)

3 (0.5/4)

0.91

1

0.3422

21

Trunk curl

0ā€“1

0 (0/0)

0 (0/0)

1.03

1

0.3112

22

Limb grasping

0ā€“1

1 (0/1)

1 (0/1)

0

1

1

23

Visual placing

0ā€“4

2 (1.25/2)

2(2/2)

0

1

1

24

Grip strength

0ā€“4

2 (2/2.75)

2 (1.25/2.75)

0

1

1

25

Body tone

0ā€“2

0 (0/1)

0 (0/1)

0.44

1

0.5073

26

Pinna reflex

0ā€“2

1 (0/1)

1 (1/1)

0

1

1

27

Corneal reflex

0ā€“3

1 (1/1)

1 (1/1)

0.36

1

0.5483

28

Toe pinch

0ā€“4

1.5 (1/2.25)

1 (0/2)

0.4

1

0.525

29

Body length

0ā€“100

90 (90/95)

90 (85.5/95)

0

1

1

30

Tail length

0ā€“100

90 (90/90)

90 (85/90)

0

1

1

31

Lacrimation

0ā€“1

0 (0/0)

0 (0/0)

0

1

1

32

Whisker morphology

0ā€“1

0 (0/0)

0 (0/0)

1.03

1

0.3112

33

Provoked biting

0ā€“1

0 (0/0)

0 (0/0.5)

1.56

1

0.2119

34

Salivation

0ā€“2

0 (0/0)

0 (0/0)

2.11

1

0.1468

35

Heart rate

0ā€“2

1 (1/1)

1 (1/1.5)

0.63

1

0.4292

36

Abdominal tone

0ā€“2

1 (0/1)

0 (0/1)

1.62

1

0.2036

37

Skin color

0ā€“2

1 (1/1)

1 (1/1)

0

1

1

38

Limb tone

0ā€“4

1.5 (0.75/2)

1 (0/1.75)

2.56

1

0.1098

39

Wire maneuver

0ā€“4

0 (0/1)

0 (0/0.5)

0.48

1

0.4902

40

Righting reflex

0ā€“3

0 (0/0)

0 (0/0)

2.11

1

0.1468

41

Contact righting

0ā€“1

1 (1/1)

1 (1/1)

0

1

1

42

Negative geotaxis

0ā€“4

0 (0/0)

0 (0/0)

0.17

1

0.6773

43

Fear to experimenter

0ā€“1

0 (0/0)

0 (0/0)

0.78

1

0.3758

44

Irritability

0ā€“1

0 (0/0)

0 (0/0)

0

1

1

45

Aggressivity

0ā€“1

0 (0/0)

0 (0/0)

1.03

1

0.3112

46

Vocalizations

0ā€“1

0 (0/1)

0 (0/0)

4.8

1

0.0285

47

Abnormal behavior

0ā€“1

0 (0/0)

0 (0/0)

0

1

1

48

Body weight

grams

27.8 (26.725/ 31.975)

27.75 (26.45/ 30.025)

0

1

1

  1. aThe table lists the medians (25%/75% interquartile) for the 48 variables in the order they were measured. The nonparametric Moodā€™s median test was used to examine statistical significance. Chi-square, degrees of freedom (d.f.) and probability (P) values are shown. We found that only the vocalizations variable was different at the P < 0.05 level.