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Figure 1 | Molecular Medicine

Figure 1

From: Female Mice Are More Susceptible to Nonalcoholic Fatty Liver Disease: Sex-Specific Regulation of the Hepatic AMP-Activated Protein Kinase-Plasminogen Activator Inhibitor 1 Cascade, but Not the Hepatic Endotoxin Response

Figure 1

Sex differences in hepatic lipid accumulation in mice with steatosis induced by feeding a 30% fructose solution. (A) Representative photomicrographs of hematoxylin and eosin staining as well as oil red O staining of liver sections (400×). (B–D) Evaluation of liver histology using the semiquantitative “Nonalcoholic steatohepatitis Clinical Research Network system for scoring activity and fibrosis in nonalcoholic fatty liver disease” (modified from (15)) (16). Data are shown as means ± SEM (n = 6). C—water (control); F—30% fructose solution; *p < 0.05 compared with respective water-fed control mice; **p < 0.01 compared with respective water-fed control mice.

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Molecular Medicine

ISSN: 1528-3658