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Figure 5 | Molecular Medicine

Figure 5

From: Female Mice Are More Susceptible to Nonalcoholic Fatty Liver Disease: Sex-Specific Regulation of the Hepatic AMP-Activated Protein Kinase-Plasminogen Activator Inhibitor 1 Cascade, but Not the Hepatic Endotoxin Response

Figure 5

Sex differences in markers of inflammation and adiponectin expression in visceral adipose tissue in mice with steatosis induced by feeding a 30% fructose solution. (A) Representative photomicrographs of immunohistochemical staining of F4/80+ cells (630x with oil immersion) and (B) number of F4/80+ cells in visceral adipose tissue of male and female mice (n = 4ā€“6 as histological material lacked). Expression levels of (C) mPGES1 (n = 5ā€“6) and (D) adiponectin (n = 6) mRNA in visceral adipose tissue of mice. Expression of mRNA was determined by real time RT-PCR with Ī²-actin as a reference gene in visceral fat. Data are shown as means Ā± SEM (n = 5ā€“6) and are specified as -fold induction. Cā€”water (control); Fā€”30% fructose solution. *p < 0.05 compared with respective water fed control mice.

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Molecular Medicine

ISSN: 1528-3658