Figure 5
From: Gene Expression Profiles in Alveolar Macrophages Induced by Lipopolysaccharide in Humans
Selected gene classifications according to biological canonical pathways. Significant regulated genes (t test false discovery rate (FDR) 0.01; n = 2,932 unique genes) from LPS samples versus saline samples were grouped according to the canonical pathways (p < 0.01) in over- or underexpression output list. The change in expression for each pathway is depicted in red for upregulation and green for downregulation. The percent of total (displayed with a gray ball) is based on the number of significantly changed genes out of the total number of genes assigned to each canonical pathway. PPAR, peroxisome proliferator-activated receptor. IRF, IFN regulatory factor; PDGF, platelet-derived growth factor.