High Mobility Group Box 1 Contributes to the Pathogenesis of Experimental Pulmonary Hypertension via Activation of Toll-like Receptor 4

Table 1 Baseline characteristics of IPAH patients.

		IPAH
	Healthy controls	All patients	Patients with hemodynamics^a
Sex (M/F)	5/10	6/15	5/11
Age (years)	40.8 ± 1.8	45.9 ± 14.6	—
mPAP (mmHg)	—	—	54.3 ± 9.4
Right atrial pressure (mmHg)	—	—	12.3 ± 6.1
Cardiac index (L/min/m²)	—	—	2.4 ± 0.8
Pulmonary capillary
wedge pressure (mmHg)	—	—	10.9 ± 3.1
6-min walk test (m)	—	328.2 ± 101.0	—

^aFive patients tested for circulating HMGB1 levels lacked right heart catheterization data. mPAP mean pulmonary artery pressure. Data represent the mean ± standard deviation.

ISSN: 1528-3658