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Figure 3 | Molecular Medicine

Figure 3

From: TH2-like Chemokine Patterns Correlate with Disease Severity in Patients with Recurrent Respiratory Papillomatosis

Figure 3

TH2-like chemokines are overexpressed in the plasma of patients with RRP and correlate with disease severity. (A) CCL17, (B) CCL18 and (C) CCL22 were measured in plasma of patients with RRP and controls. The concentration (mean ± SEM) of each chemokine is shown. Concentrations of all three chemokines are higher in patients with RRP: CCL17 pg/mL (severe 317.9 ± 84.0, mild/mod 169.7 ± 22.2, control 98.0 ± 14.3, p = 0.003); CCL18 ng/mL (severe 81.9 ± 12.8, mild/mod 72.7 ± 6.7, control 36.2 ± 8.8, p = 0.0003); and CCL22 pg/mL (severe 686.5 ± 105.1, mild/mod 512.8 ± 31.7, control 411.4 ± 34.0, p = 0.007). Levels are significantly different among patients with severe RRP (n = 10), patients with mild/moderate RRP (n = 16) and controls (n = 14), as determined by ANOVA, Kruskal-Wallis test.

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