TY - JOUR AU - Firestein, G. S. PY - 2003 DA - 2003// TI - Evolving concepts of rheumatoid arthritis JO - Nature VL - 423 UR - https://doi.org/10.1038/nature01661 DO - 10.1038/nature01661 ID - Firestein2003 ER - TY - JOUR AU - Choy, E. H. AU - Panayi, G. S. PY - 2001 DA - 2001// TI - Cytokine pathways and joint inflammation in rheumatoid arthritis JO - N. Engl. J. Med. VL - 344 UR - https://doi.org/10.1056/NEJM200103223441207 DO - 10.1056/NEJM200103223441207 ID - Choy2001 ER - TY - JOUR AU - Feldmann, M. PY - 2002 DA - 2002// TI - Development of anti-TNF therapy for rheumatoid arthritis JO - Nat. Rev. Immunol. VL - 2 UR - https://doi.org/10.1038/nri802 DO - 10.1038/nri802 ID - Feldmann2002 ER - TY - JOUR AU - Maini, R. N. PY - 2010 DA - 2010// TI - Anti-TNF therapy from the bench to the clinic: a paradigm of translational research JO - Clin. Med. VL - 10 UR - https://doi.org/10.7861/clinmedicine.10-2-161 DO - 10.7861/clinmedicine.10-2-161 ID - Maini2010 ER - TY - JOUR AU - Moreland, L. W. PY - 1999 DA - 1999// TI - Etanercept therapy in rheumatoid arthritis: a randomized, controlled trial JO - Ann. Intern. Med. VL - 130 UR - https://doi.org/10.7326/0003-4819-130-6-199903160-00004 DO - 10.7326/0003-4819-130-6-199903160-00004 ID - Moreland1999 ER - TY - JOUR AU - Cohen, S. PY - 2002 DA - 2002// TI - Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin-1 receptor antagonist, in combination with methotrexate: results of a twenty-four-week, multicenter, randomized, double-blind, placebo-controlled trial JO - Arthritis Rheum. VL - 46 UR - https://doi.org/10.1002/art.10141 DO - 10.1002/art.10141 ID - Cohen2002 ER - TY - JOUR AU - Maini, R. N. PY - 2006 DA - 2006// TI - Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate JO - Arthritis Rheum. VL - 54 UR - https://doi.org/10.1002/art.22033 DO - 10.1002/art.22033 ID - Maini2006 ER - TY - JOUR AU - Kokkola, R. PY - 2002 DA - 2002// TI - High mobility group box chromosomal protein 1: a novel proinflammatory mediator in synovitis JO - Arthritis Rheum. VL - 46 UR - https://doi.org/10.1002/art.10540 DO - 10.1002/art.10540 ID - Kokkola2002 ER - TY - JOUR AU - Taniguchi, N. PY - 2003 DA - 2003// TI - High mobility group box chromosomal protein 1 plays a role in the pathogenesis of rheumatoid arthritis as a novel cytokine JO - Arthritis Rheum. VL - 48 UR - https://doi.org/10.1002/art.10859 DO - 10.1002/art.10859 ID - Taniguchi2003 ER - TY - JOUR AU - Huttunen, H. J. AU - Fages, C. AU - Kuja-Panula, J. AU - Ridley, A. J. AU - Rauvala, H. PY - 2002 DA - 2002// TI - Receptor for advanced glycation end products-binding COOH-terminal motif of amphoterin inhibits invasive migration and metastasis JO - Cancer Res. VL - 62 ID - Huttunen2002 ER - TY - JOUR AU - Beijnum, J. R. AU - Buurman, W. A. AU - Griffioen, A. W. PY - 2008 DA - 2008// TI - Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1) JO - Angiogenesis VL - 11 UR - https://doi.org/10.1007/s10456-008-9093-5 DO - 10.1007/s10456-008-9093-5 ID - Beijnum2008 ER - TY - JOUR AU - Huang, J. S. PY - 2001 DA - 2001// TI - Role of receptor for advanced glycation end-product (RAGE) and the JAK/STAT-signaling pathway in AGE-induced collagen production in NRK-49F cells JO - J. Cell. Biochem. VL - 81 UR - https://doi.org/3.0.CO;2-Y DO - 3.0.CO;2-Y ID - Huang2001 ER - TY - JOUR AU - Zhou, Z. PY - 2008 DA - 2008// TI - HMGB1 regulates RANKL-induced osteoclastogenesis in a manner dependent on RAGE JO - J. Bone Miner. Res. VL - 23 UR - https://doi.org/10.1359/jbmr.080234 DO - 10.1359/jbmr.080234 ID - Zhou2008 ER - TY - JOUR AU - Guo, H. F. PY - 2011 DA - 2011// TI - High mobility group box 1 induces synoviocyte proliferation in rheumatoid arthritis by activating the signal transducer and activator transcription signal pathway JO - Clin. Exp. Med. VL - 11 UR - https://doi.org/10.1007/s10238-010-0116-3 DO - 10.1007/s10238-010-0116-3 ID - Guo2011 ER - TY - JOUR AU - Neeper, M. PY - 1992 DA - 1992// TI - Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins JO - J. Biol. Chem. VL - 267 UR - https://doi.org/10.1016/S0021-9258(18)42138-2 DO - 10.1016/S0021-9258(18)42138-2 ID - Neeper1992 ER - TY - JOUR AU - Hofmann, M. A. PY - 1999 DA - 1999// TI - RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides JO - Cell VL - 97 UR - https://doi.org/10.1016/S0092-8674(00)80801-6 DO - 10.1016/S0092-8674(00)80801-6 ID - Hofmann1999 ER - TY - JOUR AU - Huttunen, H. J. AU - Fages, C. AU - Rauvala, H. PY - 1999 DA - 1999// TI - Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways JO - J. Biol. Chem. VL - 274 UR - https://doi.org/10.1074/jbc.274.28.19919 DO - 10.1074/jbc.274.28.19919 ID - Huttunen1999 ER - TY - JOUR AU - Malherbe, P. PY - 1999 DA - 1999// TI - cDNA cloning of a novel secreted isoform of the human receptor for advanced glycation end products and characterization of cells co-expressing cell-surface scavenger receptors and Swedish mutant amyloid precursor protein JO - Brain Res. Mol. Brain Res. VL - 71 UR - https://doi.org/10.1016/S0169-328X(99)00174-6 DO - 10.1016/S0169-328X(99)00174-6 ID - Malherbe1999 ER - TY - JOUR AU - Park, I. H. PY - 2004 DA - 2004// TI - Expression of a novel secreted splice variant of the receptor for advanced glycation end products (RAGE) in human brain astrocytes and peripheral blood mononuclear cells JO - Mol. Immunol. VL - 40 UR - https://doi.org/10.1016/j.molimm.2003.11.027 DO - 10.1016/j.molimm.2003.11.027 ID - Park2004 ER - TY - JOUR AU - Yonekura, H. PY - 2003 DA - 2003// TI - Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury JO - Biochem. J. VL - 370 UR - https://doi.org/10.1042/bj20021371 DO - 10.1042/bj20021371 ID - Yonekura2003 ER - TY - JOUR AU - Yonekura, H. AU - Yamamoto, Y. AU - Sakurai, S. AU - Watanabe, T. AU - Yamamoto, H. PY - 2005 DA - 2005// TI - Roles of the receptor for advanced glycation endproducts in diabetes-induced vascular injury JO - J. Pharmacol. Sci. VL - 97 UR - https://doi.org/10.1254/jphs.CPJ04005X DO - 10.1254/jphs.CPJ04005X ID - Yonekura2005 ER - TY - JOUR AU - Kasugai, S. AU - Fujisawa, R. AU - Waki, Y. AU - Miyamoto, K. AU - Ohya, K. PY - 2000 DA - 2000// TI - Selective drug delivery system to bone: small peptide (Asp)6 conjugation JO - J. Bone Miner. Res. VL - 15 UR - https://doi.org/10.1359/jbmr.2000.15.5.936 DO - 10.1359/jbmr.2000.15.5.936 ID - Kasugai2000 ER - TY - JOUR AU - Yokogawa, K. PY - 2001 DA - 2001// TI - Selective delivery of estradiol to bone by aspartic acid oligopeptide and its effects on ovariectomized mice JO - Endocrinology VL - 142 UR - https://doi.org/10.1210/endo.142.3.8024 DO - 10.1210/endo.142.3.8024 ID - Yokogawa2001 ER - TY - JOUR AU - Takahashi, T. PY - 2008 DA - 2008// TI - Bone-targeting of quinolones conjugated with an acidic oligopeptide JO - Pharm. Res. VL - 25 UR - https://doi.org/10.1007/s11095-008-9605-4 DO - 10.1007/s11095-008-9605-4 ID - Takahashi2008 ER - TY - JOUR AU - Oldberg, A. AU - Franzén, A. AU - Heinegård, D. PY - 1986 DA - 1986// TI - Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence JO - Proc. Natl. Acad. Sci. U. S. A. VL - 83 UR - https://doi.org/10.1073/pnas.83.23.8819 DO - 10.1073/pnas.83.23.8819 ID - Oldberg1986 ER - TY - JOUR AU - Butler, W. T. PY - 1989 DA - 1989// TI - The nature and significance of osteopontin JO - Connect Tissue Res. VL - 23 UR - https://doi.org/10.3109/03008208909002412 DO - 10.3109/03008208909002412 ID - Butler1989 ER - TY - JOUR AU - Nishioka, T. PY - 2006 DA - 2006// TI - Enhancement of drug delivery to bone: characterization of human tissue-nonspecific alkaline phosphatase tagged with an acidic oligopeptide JO - Mol. Genet. Metab. VL - 88 UR - https://doi.org/10.1016/j.ymgme.2006.02.012 DO - 10.1016/j.ymgme.2006.02.012 ID - Nishioka2006 ER - TY - JOUR AU - Millán, J. L. PY - 2008 DA - 2008// TI - Enzyme replacement therapy for murine hypophosphatasia JO - J. Bone Miner. Res. VL - 23 UR - https://doi.org/10.1359/jbmr.071213 DO - 10.1359/jbmr.071213 ID - Millán2008 ER - TY - JOUR AU - Montaño, A. M. PY - 2008 DA - 2008// TI - Acidic amino acid tag enhances response to enzyme replacement in mucopolysaccharidosis type VII mice JO - Mol. Genet. Metab. VL - 94 UR - https://doi.org/10.1016/j.ymgme.2008.01.007 DO - 10.1016/j.ymgme.2008.01.007 ID - Montaño2008 ER - TY - JOUR AU - Tomatsu, S. PY - 2010 DA - 2010// TI - Enhancement of drug delivery: enzyme-replacement therapy for murine Morquio A syndrome JO - Mol. Ther. VL - 18 UR - https://doi.org/10.1038/mt.2010.32 DO - 10.1038/mt.2010.32 ID - Tomatsu2010 ER - TY - JOUR AU - Whyte, M. P. PY - 2012 DA - 2012// TI - Enzyme-replacement therapy in life-threatening hypophosphatasia JO - N. Engl. J. Med. VL - 366 UR - https://doi.org/10.1056/NEJMoa1106173 DO - 10.1056/NEJMoa1106173 ID - Whyte2012 ER - TY - JOUR AU - Trentham, D. E. AU - Townes, A. S. AU - Kang, A. H. PY - 1977 DA - 1977// TI - Autoimmunity to type II collagen an experimental model of arthritis JO - J. Exp. Med. VL - 146 UR - https://doi.org/10.1084/jem.146.3.857 DO - 10.1084/jem.146.3.857 ID - Trentham1977 ER - TY - JOUR AU - Courtenay, J. S. AU - Dallman, M. J. AU - Dayan, A. D. AU - Martin, A. AU - Mosedale, B. PY - 1980 DA - 1980// TI - Immunisation against heterologous type II collagen induces arthritis in mice JO - Nature VL - 283 UR - https://doi.org/10.1038/283666a0 DO - 10.1038/283666a0 ID - Courtenay1980 ER - TY - JOUR AU - Williams, R. O. AU - Feldmann, M. AU - Maini, R. N. PY - 1992 DA - 1992// TI - Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis JO - Proc. Natl. Acad. Sci. U. S. A. VL - 89 UR - https://doi.org/10.1073/pnas.89.20.9784 DO - 10.1073/pnas.89.20.9784 ID - Williams1992 ER - TY - JOUR AU - Neurath, M. F. PY - 1999 DA - 1999// TI - Methotrexate specifically modulates cytokine production by T cells and macrophages in murine collagen-induced arthritis (CIA): a mechanism for methotrexatemediated immunosuppression JO - Clin. Exp. Immunol. VL - 115 UR - https://doi.org/10.1046/j.1365-2249.1999.00753.x DO - 10.1046/j.1365-2249.1999.00753.x ID - Neurath1999 ER - TY - JOUR AU - Hori, O. PY - 1995 DA - 1995// TI - The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin: mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system JO - J. Biol. Chem. VL - 270 UR - https://doi.org/10.1074/jbc.270.43.25752 DO - 10.1074/jbc.270.43.25752 ID - Hori1995 ER - TY - JOUR AU - Park, J. S. PY - 2006 DA - 2006// TI - High mobility group box 1 protein interacts with multiple Toll-like receptors JO - Am. J. Physiol. Cell Physiol. VL - 290 UR - https://doi.org/10.1152/ajpcell.00401.2005 DO - 10.1152/ajpcell.00401.2005 ID - Park2006 ER - TY - JOUR AU - Hofmann, M. A. PY - 2002 DA - 2002// TI - RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response JO - Genes Immun. VL - 3 UR - https://doi.org/10.1038/sj.gene.6363861 DO - 10.1038/sj.gene.6363861 ID - Hofmann2002 ER - TY - JOUR AU - Foell, D. PY - 2003 DA - 2003// TI - Expression of the pro-inflammatory protein S100A12 (EN-RAGE) in rheumatoid and psoriatic arthritis JO - Rheumatology (Oxford) VL - 42 UR - https://doi.org/10.1093/rheumatology/keg385 DO - 10.1093/rheumatology/keg385 ID - Foell2003 ER - TY - JOUR AU - Chen, Y. S. AU - Yan, W. AU - Geczy, C. L. AU - Brown, M. A. AU - Thomas, R. PY - 2009 DA - 2009// TI - Serum levels of soluble receptor for advanced glycation end products and of S100 proteins are associated with inflammatory, autoantibody, and classical risk markers of joint and vascular damage in rheumatoid arthritis JO - Arthritis Res. Ther. VL - 11 UR - https://doi.org/10.1186/ar2645 DO - 10.1186/ar2645 ID - Chen2009 ER - TY - JOUR AU - Lent, P. L. PY - 2008 DA - 2008// TI - Stimulation of chondrocyte-mediated cartilage destruction by S100A8 in experimental murine arthritis JO - Arthritis Rheum. VL - 58 UR - https://doi.org/10.1002/art.24074 DO - 10.1002/art.24074 ID - Lent2008 ER - TY - JOUR AU - Turovskaya, O. PY - 2008 DA - 2008// TI - RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis JO - Carcinogenesis VL - 29 UR - https://doi.org/10.1093/carcin/bgn188 DO - 10.1093/carcin/bgn188 ID - Turovskaya2008 ER - TY - JOUR AU - Srikrishna, G. PY - 2010 DA - 2010// TI - Carboxylated N-glycans on RAGE promote S100A12 binding and signaling JO - J. Cell. Biochem. VL - 110 UR - https://doi.org/10.1002/jcb.22575 DO - 10.1002/jcb.22575 ID - Srikrishna2010 ER - TY - JOUR AU - Srikrishna, G. PY - 2002 DA - 2002// TI - N-Glycans on the receptor for advanced glycation end products influence amphoterin binding and neurite outgrowth JO - J. Neurochem. VL - 80 UR - https://doi.org/10.1046/j.0022-3042.2002.00796.x DO - 10.1046/j.0022-3042.2002.00796.x ID - Srikrishna2002 ER - TY - JOUR AU - Lipsky, P. E. PY - 2000 DA - 2000// TI - Infliximab and methotrexate in the treatment of rheumatoid arthritis: AntiTumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group JO - N. Engl. J. Med. VL - 343 UR - https://doi.org/10.1056/NEJM200011303432202 DO - 10.1056/NEJM200011303432202 ID - Lipsky2000 ER - TY - JOUR AU - Weinblatt, M. E. PY - 2003 DA - 2003// TI - Adalimumab, a fully human anti-tumor necrosis factor alpha monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the ARMADA trial JO - Arthritis Rheum. VL - 48 UR - https://doi.org/10.1002/art.10697 DO - 10.1002/art.10697 ID - Weinblatt2003 ER - TY - JOUR AU - Campbell, I. K. AU - O’Donnell, K. AU - Lawlor, K. E. AU - Wicks, I. P. PY - 2001 DA - 2001// TI - Severe inflammatory arthritis and lymphadenopathy in the absence of TNF JO - J. Clin. Invest. VL - 107 UR - https://doi.org/10.1172/JCI12724 DO - 10.1172/JCI12724 ID - Campbell2001 ER - TY - JOUR AU - Pullerits, R. AU - Jonsson, I. M. AU - Kollias, G. AU - Tarkowski, A. PY - 2008 DA - 2008// TI - Induction of arthritis by high mobility group box chromosomal protein 1 is independent of tumour necrosis factor signalling JO - Arthritis Res. Ther. VL - 10 UR - https://doi.org/10.1186/ar2445 DO - 10.1186/ar2445 ID - Pullerits2008 ER - TY - JOUR AU - Saijo, S. AU - Asano, M. AU - Horai, R. AU - Yamamoto, H. AU - Iwakura, Y. PY - 2002 DA - 2002// TI - Suppression of autoimmune arthritis in interleukin-1-deficient mice in which T cell activation is impaired due to low levels of CD40 ligand and OX40 expression on T cells JO - Arthritis Rheum. VL - 46 UR - https://doi.org/10.1002/art.10172 DO - 10.1002/art.10172 ID - Saijo2002 ER - TY - JOUR AU - Alonzi, T. PY - 1998 DA - 1998// TI - Interleukin 6 is required for the development of collagen-induced arthritis JO - J. Exp. Med. VL - 187 UR - https://doi.org/10.1084/jem.187.4.461 DO - 10.1084/jem.187.4.461 ID - Alonzi1998 ER -