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Table 5 Changes in the expression of zebrafish proenkephalins and proopiomelanocortin in dre-oprm1 morphants.

From: In Vivo Regulation of the μ Opioid Receptor: Role of the Endogenous Opioid Agents

  dre-penk a dre-penk b dre-pomc a
24 hpf 1.37 ± 0.04a 1.54 ± 0.14a 1.03 ± 0.29
48 hpf 0.54 ± 0.10a 0.98 ± 0.04 0.88 ± 0.20
  1. Results represent the relative gene expression fold-changes of dre-penk a, dre-penk b and dre-pomc a in morpholino-injected embryos of 24 and 48 hpf. Data shown are normalized to dre-eef1a1l1. Note the differential regulation of enkephalin- and β-END-containing genes in the morphant embryos. A total of 50 embryos were used for each treatment and for each time point; the experiment was performed in triplicate and repeated four times.
  2. ap < 0.05 (unpaired Student t test, n = 4).