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Figure 5 | Molecular Medicine

Figure 5

From: Dysfunction of Inflammation-Resolving Pathways Is Associated with Exaggerated Postoperative Cognitive Decline in a Rat Model of the Metabolic Syndrome

Figure 5

M1 macrophages were elevated and proresolving α7 nAChR+CD11b/c+ cells were decreased in the spleen of LCR rats. (A) CD11b/c was used as a marker to analyze M1 macrophages splenocytes by flow cytometry in LCR and HCR rats under sham and surgical conditions at d 3. (B) Absolute number of M1 macrophages in each spleen was calculated by multiplying the percentage of CD11b/c+ cells by total number of splenocytes at d 3; n = 3 in each group. **p = 0.01 versus LCR sham. (C) Flow cytometry was used to analyze α7 nAChR+CD11b/c+ cells in the splenocytes. Values are means ± SD.

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