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Figure 2 | Molecular Medicine

Figure 2

From: Molecular Expression and Characterization of Erythroid-Specific 5-Aminolevulinate Synthase Gain-of-Function Mutations Causing X-Linked Protoporphyria

Figure 2

SDS-PAGE and predicted amino-terminal sequence comparisons. SDS-PAGE of wild-type and mutant ALAS2 proteins after purification to homogeneity by affinity chromatography and gel filtration chromatography. (A) Lanes 1 and 8: protein molecular weight standards; lanes 2 and 7: wild-type ALAS2; lane 3: Δ93 p.F557X carboxy-terminal truncation polypeptide; lane 4: ΔAT polypeptide; lane 5: ΔG polypeptide; lane 6: ΔAGTG polypeptide. (B) Lane 1: protein molecular weight standard; lane 2: wild-type ALAS2; lane 3: p.Q581X truncation polypeptide.

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Molecular Medicine

ISSN: 1528-3658