Figure 3From: Preclinical Studies in the mdx Mouse Model of Duchenne Muscular Dystrophy with the Histone Deacetylase Inhibitor GivinostatGivinostat increases the size of mdx muscles. (A) Representative images of hematoxylin and eosin staining (H&E) of tibialis anterior (TA) transverse sections of CTR-, TSA- or givinostat-treated mdx mice (givinostat 1 mg/kg/d = ITF1; givinostat 5mg/kg/d = ITF5; givinostat 10 mg/kg/kg = ITF10) at the end of the treatment. Original magnification, 10x. (B) Graph of the analysis of myofiber CSA of muscles represented in (A). Data are represented as average ± SEM; n = 6. *p < 0.05; **p < 0.01; ***p < 0.001.Back to article page