Givinostat increases the size of mdx muscles. (A) Representative images of hematoxylin and eosin staining (H&E) of tibialis anterior (TA) transverse sections of CTR-, TSA- or givinostat-treated mdx mice (givinostat 1 mg/kg/d = ITF1; givinostat 5mg/kg/d = ITF5; givinostat 10 mg/kg/kg = ITF10) at the end of the treatment. Original magnification, 10x. (B) Graph of the analysis of myofiber CSA of muscles represented in (A). Data are represented as average ± SEM; n = 6. *p < 0.05; **p < 0.01; ***p < 0.001.