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Figure 6 | Molecular Medicine

Figure 6

From: Preclinical Studies in the mdx Mouse Model of Duchenne Muscular Dystrophy with the Histone Deacetylase Inhibitor Givinostat

Figure 6

Givinostat reduces inflammation (neutrophil granulocytes) in mdx mice. Representative images of MPO staining on TA transverse sections of CTR-, TSA-, or givinostat-treated mdx mice (givinostat 1 mg/kg/d = ITF1; givinostat 5 mg/kg/d = ITF5; givinostat 10 mg/kg/kg = ITF10). Original magnification, 10x. (B) Graph representing MPO evaluation scored as the number of MPO-positive cells per field. Data are presented as the average ± SEM; n = 6. **p < 0.01.

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