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Figure 7 | Molecular Medicine

Figure 7

From: Preclinical Studies in the mdx Mouse Model of Duchenne Muscular Dystrophy with the Histone Deacetylase Inhibitor Givinostat

Figure 7

Givinostat ameliorates fatigue resistance of mdx mice. Treadmill test on CTR-, TSA-, or givinostat-treated mdx mice (givinostat 1 mg/kg/d = ITF1; givinostat 5 mg/kg/d = ITF5; givinostat 10 mg/kg/kg = ITF10) at four time points during the treatment from d 0 to d 105 (1 = d 0; 2 = 1 month; 3 = 2 months; 4 = 3.5 months). Data are presented as the average ± SEM; n = 8. *p < 0.05; **p < 0.01.

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