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Figure 1 | Molecular Medicine

Figure 1

From: Genetic Markers of a Munc13 Protein Family Member, BAIAP3, Are Gender Specifically Associated with Anxiety and Benzodiazepine Abuse in Mice and Humans

Figure 1

Immunofluorescence analysis of Baiap3 expression in mouse brain. (A) Sagittal brain section of adult Baiap3 WT mouse stained with rabbit anti-Baiap3 antibody. (B) Sagittal brain section of adult Baiap3 KO littermate showing the absence of Baiap3 immunoreactivity. Please note that the signal observed in the hippocampus of both WT and KO brain is a nonspecific background staining. (C) Coronal brain section of adult WT mouse stained for Baiap3 with a corresponding coronal diagram, adapted from the mouse Paxinos brain atlas (Bregma −1.46). PB, parabrachial nucleus; NTS, nucleus tractus solitarius; Hi, hippocampus; SC, superior colliculus; IC, inferior colliculus; PAG, periaqueductal gray; LS, lateral septum; Th, thalamus; Hy, hypothalamus; BST, bed nucleus of the stria terminalis; PV, paraventricular thalamic nucleus; DM, dorsomedial hypothalamic nucleus; VMH, ventromedial hypothalamic nucleus; Arc, arcuate nucleus; Ce, central amygdaloid nucleus; BLA, basolateral amygdaloid nucleus, anterior part; BMA, basomedial amygdaloid nucleus, anterior part; ME, medial amygdaloid nucleus; ACo, anterior cortical amygdaloid nucleus. Scale bars equal 1 mm.

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Molecular Medicine

ISSN: 1528-3658