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Figure 6 | Molecular Medicine

Figure 6

From: Suppression of Coronary Atherosclerosis by Helix B Surface Peptide, a Nonerythropoietic, Tissue-Protective Compound Derived from Erythropoietin

Figure 6

HBSP reduces the number and polarization of macrophages and increases IL-10 expression in coronary atherosclerotic lesions of WHHLMI rabbits. HBSP reduces the number of macrophages (A: F4/80-positive cells), M1 macrophages (B: CD11c-positive cells) and M1/M2 macrophage ratio (C) and increases IL-10-positive cells (D). Data are mean ± SEM; negative control IgG, n = 3; control, n = 7; HBSP, n = 8; *P< 0.01, #P< 0.05.

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Molecular Medicine

ISSN: 1528-3658