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Figure 5 | Molecular Medicine

Figure 5

From: Low-Dose T3 Replacement Restores Depressed Cardiac T3 Levels, Preserves Coronary Microvasculature and Attenuates Cardiac Dysfunction in Experimental Diabetes Mellitus

Figure 5

LV Deiodinase Expression. (A) LV DIO3 staining in control and diabetic hearts at 2x magnification. (B) DIO3 IHC protein quantification. Values represented as the percentage of DIO3 staining versus the total tissue area. (C) DIO2, type 2 deiodinase mRNA expression. (D) DIO3, type 3 deiodinase mRNA expression. Gene expression values represented as means (SD). Gene expression was normalized using the housekeeping genes cyclophilin A and Rplp 1; n = 3–5/group. *p < 0.05 versus control; †p < 0.05 versus STZ/N.

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