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Table 1 Characteristics of patients with COPD and healthy controls whose tissue was used for histological analysis.

From: Midkine Is Expressed and Differentially Processed during Chronic Obstructive Pulmonary Disease Exacerbations and Ventilator-Associated Pneumonia Associated with Staphylococcus aureus Infection

 

Controls

COPD GOLD IV

Sex (M/F, n)

2/7, 9

5/6, 11

Agea (years)

63 (33–76)

58.5 (53–66)

Pack-yearsa (years)

0

40.7 (2560)

Exsmokers/current smokers

0

11/0

GCS (yes/no/unknown)

0

10/0/1b

β2 Agonist (yes/no/unknown)

0

10/0/1b

Lung function

  

FEV1a

2.7 (1.7–5.1)

0.6 (0.4–1.0)

FEV1/(F)VCa

85.9 (66–121)

30.2 (17–39)

FEV1 % of predicteda

109.8 (82–141)

21.4 (13–27)

  1. FEV1, forced expiratory volume; (F)VC, (forced) vital capacity; GCS, inhaled glucocorticosteroids.
  2. aData are given as mean (range).
  3. bn = 11; one subject with missing medical history