Table 3 Univariate and multivariable analysis of factors associated with sufficient LN sampling (≥12 nodes).
LN <12 | LN ≥12 | Adjusted | ||||
|---|---|---|---|---|---|---|
(n (%)) | (n (%)) | OR (95% CI) | P a | OR (95% CI)b | P a | |
Sex | 0.6 (0.3–1.1) | 0.089 | 0.3 (0.7–2.6) | 0.329 | ||
Female | 33 (28) | 83 (72) | ||||
Male | 35 (40) | 53 (60) | ||||
Age (years) | 0.6 (0.3–1.1) | 0.110 | 0.6 (0.3–1.1) | 0.061 | ||
<75 | 24 (27) | 64 (73) | ||||
≥75 | 44 (38) | 72 (62) | ||||
Stage | 1.4 (0.7–2.8) | 0.280 | — | NA | ||
I and II | 51 (36) | 92 (64) | ||||
III | 17 (28) | 44 (72) | ||||
Histology grade | 1.4 (0.7–2.8) | 0.279 | — | NA | ||
High | 53 (36) | 94 (64) | ||||
Low | 16 (28) | 41 (72) | ||||
Tumor size (cm)c | 1.8 (1.0–3.3) | 0.045 | 1.6 (0.7–3.5) | 0.099 | ||
<5 | 35 (41) | 50 (59) | ||||
≥5 | 33 (28) | 86 (72) | ||||
Tumor invasion | 1.5 (0.7–2.9) | 0.343 | — | NA | ||
pT1-2 | 18 (39) | 28 (61) | ||||
pT3–4 | 50 (32) | 108 (68) | ||||
MSI status | 2.5 (1.2–4.9) | 0.008 | 2.3 (0.9–6.3) | 0.223 | ||
MSS | 54 (39) | 83 (61) | ||||
MSI | 14 (21) | 53 (79) | ||||
KRAS status | 1.1 (0.6–2.0) | 0.758 | — | NA | ||
Wild-type | 44 (34) | 85 (66) | ||||
Mutated | 24 (32) | 51 (68) | ||||
BRAFstatus | 1.4 (0.7–2.8) | 0.306 | — | NA | ||
Wild-type | 52 (36) | 94 (64) | ||||
Mutated | 16 (28) | 41 (72) | ||||
Location in colon | 2.9 (1.5–5.5) | 0.001 | 2.4 (1.2–4.9) | 0.014 | ||
Proximal | 39 (27) | 106 (73) | ||||
Distal | 30 (51) | 29 (49) |