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Figure 1 | Molecular Medicine

Figure 1

From: Peptides That Bind Specifically to an Antibody from a Chronic Lymphocytic Leukemia Clone Expressing Unmutated Immunoglobulin Variable Region Genes

Figure 1

(A) Domain architecture of an IgG1 mAb and the surface membrane IgM of a BCR. (B) Polyclonal phage ELISA of R0–R4 populations, as well as K07 control phage, against U-CLL mAb068. The R3 and R4 populations also were tested against wells containing the negative control protein HSA (gray). CH: immunoglobulin heavy chain constant region; CL: Immunoglobulin light chain constant region; CH1, CH2, CH3, and CH4: immunoglobulin constant region heavy chains 1, 2, 3, and 4, respectively; VL: immunoglobulin light chain variable region; VH: immunoglobulin heavy chain variable region.

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Molecular Medicine

ISSN: 1528-3658