Peptides That Bind Specifically to an Antibody from a Chronic Lymphocytic Leukemia Clone Expressing Unmutated Immunoglobulin Variable Region Genes

Table 3 Peptides synthesized for in vitro analysis.^a

Peptide^a	Sequence	K _D ^b	Selection target (comment)
D4-Btn	DYCNLSVSWCYP-K (Btn)	ND	U-CLL mAb 068 (this work; family 2)
D4-3K	DYCNLSVSWCYP-GSGKKK	NB	U-CLL mAb 068 (this work; family 2)
D2-Btn	VSCNPFSWLPRCYA-K (Btn)	ND	U-CLL mAb 068 (this work; family 5)
D2-3K	VSCNPFSWLPRCYA-GSGKKK	58 µmol/L	U-CLL mAb 068 (this work; family 5)
E6-Btn	FPCWALPSQYLCRP-K (Btn)	ND	U-CLL mAb 068 (this work)
E6-3K	FPCWALPSQYLCRP-GSGKKK	111 µmol/L	U-CLL mAb 068 (this work)
PhD-068-4-Btn	WPLWSIPPFSPR-K (Btn)	weak	U-CLL mAb 068 (reference [5])
PhD-068-4-3K	WPLWSIPPFSPR-KKKK	weak	U-CLL mAb 068 (reference [5])
PhD-169-8-Btn	DNYAAALAQRAR-K (Btn)	ND	M-CLL mAb 169 (reference [5])
PhD-169-8-4K	DNYAAALAQRAR-KKKK	31 nmol/L	M-CLL mAb 169 (reference [5])

ISSN: 1528-3658