Skip to main content

Table 2 Effect of DT18 on mouse well-being and tissue index.

From: Antiangiogenic and Antitumoral Effects Mediated by a Vascular Endothelial Growth Factor Receptor 1 (VEGFR-1)-Targeted DNAzyme

Groups

Body weight gain (g)

Diet intake (g/d)

Liver index (mg/g)

Lung index (mg/g)

Spleen index (mg/g)

Renal index (mg/g)

Saline

1.71 ± 0.96

38.34 ± 5.09

48.33 ± 3.44

14.15 ± 1.45

4.02 ± 0.50

6.43 ± 0.44

INV-Ctrl

2.44 ± 0.58

42.39 ± 3.47

48.58 ± 3.20

13.67 ± 2.11

3.93 ± 0.72

6.44 ± 0.72

DT18

1.77 ± 0.91

39.01 ± 5.32

47.53 ± 2.98

13.60 ± 1.78

4.24 ± 1.05

6.37 ± 1.01

F value

2.362

2.976

0.292

0.276

0.404

0.025

P value

0.113

0.063

0.749

0.761

0.672

0.976

  1. Data are expressed as mean ± SE and analyzed by one-way ANOVA followed by the Dunnett test (n = 5).
Back to article page

Molecular Medicine

ISSN: 1528-3658