| DT18 PK parameters |
---|
Dose (mg/kg) | T1/2α (h) | T1/2β (h) | Cmax(mg/mL) | AUC (mg/mL h) | Vd (mL/kg) |
---|
10 | 0.1 | 46.7 | 84.4 | 97 | 890 |
- The two-compartmental model of intravenous bolus injection best fit the plasma concentration-time curve. T1/2α, distribution half-life; T1/2β, elimination half-life; Cmax, maximum concentration; AUC, area under the curve; Vd, volume of distribution.