Figure 4

Effect of iodine on histology of normal or tumoral prostate. Iodine was supplemented for 12 or 24 wks. Representative images of prostates stained with hematoxylineosin are shown (magnification 20×). Histopathology analysis was made according to the criteria proposed by Kaplan-Lefko et al. (29). The percentage of acini with pathological lesions (PIN and well-differentiated cancer) is shown. Data were analyzed by using a two-way ANOVA, followed by a Bonferroni post hoc test. No significant differences were found between groups. n.d., Not detected; n = 4−6 per group.