Skip to main content
Figure 2 | Molecular Medicine

Figure 2

From: Increased Expression and Activation of Absent in Melanoma 2 Inflammasome Components in Lymphocytic Infiltrates of Abdominal Aortic Aneurysms

Figure 2

Representative examples of grade 3 AAA. Lobular arranged VALT at the adventitia/media border was characterized as tertiary lymphoid organs (TLA) by immunolabeling of monocytes/macrophages (CD68), T cells (CD3), B cells (CD20), activated B cells and lymphatic endothelium (D2-40, identifying the highest developmental grade of TLA). The inflammasome components ASC, AIM2, caspase-1 and caspase-5 were identified in lymphoid cells derived from different compartments within the TLAs. A, adventitia; M, media; original magnification, 200x.

Back to article page

Molecular Medicine

ISSN: 1528-3658