Skip to main content
Figure 6 | Molecular Medicine

Figure 6

From: Binge Alcohol Consumption Aggravates Oxidative Stress and Promotes Pathogenesis of NASH from Obesity-Induced Simple Steatosis

Figure 6

Immunohistochemical staining of 4-HNE in the liver tissues from OLETF and OLET rats without and with ethanol (EtOH) treatment. The images are representative of eight rats per group. (A) Marked increase in the staining intensity of 4-HNE in both untreated and ethanol-treated OLETF rats compared with OLET rats. There were enormous amounts of 4-HNE adduct aggresomes within hepatocytes (arrow). (B) Quantitative data of HNE staining intensity. Data are mean ± SD of eight rats per group. P < 0.001, untreated versus all groups of ethanol-treated OLETF rats. Original magnification 100×.

Back to article page

Molecular Medicine

ISSN: 1528-3658