Table 1 Baseline patient characteristics.^a

Subjects

24

24

Males/females

18/6

12/12

Weight (kg)

92.2 ± 3.8

91.7 ± 2.7

Age

63.0 ± 1.5

63.8 ± 1.4

Height (cm)

175.3 ± 1.8

171.0 ± 1.6

BMI

29.9 ± 1.0

31.4 ± 0.8

ARA 290 dose (mcg/kg)

45.0 ± 1.9

0

ARA 290 dose (mg/ m²)

1.9 ± 0.05

0

hs-CRP^b

3.35 ± 0.86

3.73 ± 1.17

Hb A_1c(%; mmol/mol)^c

7.3 ± 0.4; 55.8 ± 4.4

6.9 ± 0.2; 51.7 ± 1.9

(5.4%, 6.6%, 12.3%)

(5.8%, 6.7%, 9.3%)

Cholesterol (mmol/L)

4.57 ± 0.18

4.59 ± 0.15

HDL (mmol/L)

1.22 ± 0.09

1.35 ± 0.08

Triglycerides (mmol/L)

2.35 ± 0.25

2.30 ± 0.27

SFNSL total score

24.8 ± 2.5 (3, 25, 52)

21.3 ± 1.7 (7, 21, 38)

RAND-36

NPSI total score

17.0 ± 2.0 (0, 16.5, 33.3)

21.7 ± 2.0 (4.5, 22.8, 37.5)

PainDetect total score

18.0 ± 1.4 (6, 20, 27)

18.0 ± 1.3 (6, 20, 28)

6MWT (m)

410.3 ± 17.4

447.8 ± 19.6

6MWT predicted (m)^c

656.0 ± 13.8

618.4 ± 13.6

CNFD (number/mm²)

24.8 ± 1.4

24.1 ± 1.7