Figure 5
From: Widespread Expression of Erythropoietin Receptor in Brain and Its Induction by Injury
EPOR upregulation in neurons and oligodendrocytes of the hippocampal formation of a patient suffering from temporomesial complex-focal epilepsy as demonstrated by immunohistochemistry using ctEPOR-AB. (A) Overview of the surgical sample stained with ctEPOR-AB. (B) Upregulation of EPOR, visualized by brown color of the AEC-chromogen, in some (arrows) but not all (arrow heads) neurons of the CA1 region. (C) EPOR positive neurons in the CA4 region (arrows). (D) Dentate gyrus neurons (arrows) expressing EPOR. (E) EPOR positive oligodendrocytes (arrows) as well as endothelial cells of capillaries (arrow heads) in the adjacent white matter. (F) No staining was observed when omitting the primary antibody.