Skip to main content
Figure 4 | Molecular Medicine

Figure 4

From: AMP-Activated Protein Kinase and Glycogen Synthase Kinase 3β Modulate the Severity of Sepsis-induced Lung injury

Figure 4

(A,B) Metformin prevents the loss of mitochondrial ETC complex V and increased ETC complexes III and IV in lungs of mice subjected to sepsis-induced ALI. (A) Representative Western blots and (B) quantitative data show the amount of ETC complexes I-V in control (sham), hemorrhage/CLP- or metformin and hemorrhage/CLP-treated mice (means ± SD, n = 3, *p < 0.05). Comp. I: NDUFB8; Comp. II: 30 kDa FeS complex; Comp. III: Core protein 2; Comp. IV: subunit I; Comp. V: α subunit.

Back to article page

Molecular Medicine

ISSN: 1528-3658