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Figure 4 | Molecular Medicine

Figure 4

From: Mechanical Ventilation Augments Poly(I:C)-Induced Lung Injury via a WISP1-Integrin β3-Dependent Pathway in Mice

Figure 4

Effects of anti-WISP1 treatment on (A) EBA permeability, (B) wet:dry ratio of lungs, and (C) levels of total protein, (D) TNF-α and (E) IL-6, as well as (F) PMNs numbers in BALF at 4 h after poly(I:C) and MTV treatment. Animals received the anti-WISP1 blocking antibody or control IgG i.p. 1 h before mechanical ventilation. Data are presented as mean ± SEM (n = 10) and compared by paired t test. For comparing the anti-WISP1 group with the IgG group *P < 0.05, **P < 0.01.

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Molecular Medicine

ISSN: 1528-3658