Figure 1
From: HMGB1 Mediates Anemia of Inflammation in Murine Sepsis Survivors
Sepsis survivors develop sustained anemia, as well as a delayed elevation in HMGB1. Mice were subject to CLP to induce severe sepsis, or sham surgery as control. Compete blood counts were performed at prespecified time points (A–F). TNF (G) and IL-6 (H) were measured by multiplex ELISA. HMGB1 was determined by semiquantitative immunoblotting (I). Data are expressed as mean ± SD (n = 4−5 mice/group). *p < 0.05, **p < 0.01, ***p < 0.001 versus sham.