TY - JOUR AU - Selkoe, D. J. PY - 2001 DA - 2001// TI - Alzheimer’s disease: Genes, proteins, and therapy JO - Physiol. Rev. VL - 81 UR - https://doi.org/10.1152/physrev.2001.81.2.741 DO - 10.1152/physrev.2001.81.2.741 ID - Selkoe2001 ER - TY - JOUR AU - Masters, C. L. PY - 1985 DA - 1985// TI - Amyloid plaque core protein in Alzheimer disease and Down syndrome JO - Proc. Natl. Acad. Sci. U. S. A. VL - 82 UR - https://doi.org/10.1073/pnas.82.12.4245 DO - 10.1073/pnas.82.12.4245 ID - Masters1985 ER - TY - JOUR AU - Goedert, M. AU - Wischik, C. M. AU - Crowther, R. A. AU - Walker, J. E. AU - Klug, A. PY - 1988 DA - 1988// TI - Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: Identification as the microtubule-associated protein tau JO - Proc. Natl. Acad. Sci. U. S. A. VL - 85 UR - https://doi.org/10.1073/pnas.85.11.4051 DO - 10.1073/pnas.85.11.4051 ID - Goedert1988 ER - TY - JOUR AU - Caccamo, A. AU - Majumder, S. AU - Richardson, A. AU - Strong, R. AU - Oddo, S. PY - 2010 DA - 2010// TI - Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: Effects on cognitive impairments JO - J. Biol. Chem. VL - 285 UR - https://doi.org/10.1074/jbc.M110.100420 DO - 10.1074/jbc.M110.100420 ID - Caccamo2010 ER - TY - JOUR AU - Hardy, J. A. AU - Higgins, G. A. PY - 1992 DA - 1992// TI - Alzheimer’s disease: The amyloid cascade hypothesis JO - Science VL - 256 UR - https://doi.org/10.1126/science.1566067 DO - 10.1126/science.1566067 ID - Hardy1992 ER - TY - JOUR AU - Sakono, M. AU - Zako, T. PY - 2010 DA - 2010// TI - Amyloid oligomers: Formation and toxicity of Abeta oligomers JO - FEBS J. VL - 277 UR - https://doi.org/10.1111/j.1742-4658.2010.07568.x DO - 10.1111/j.1742-4658.2010.07568.x ID - Sakono2010 ER - TY - JOUR AU - Pagani, L. AU - Eckert, A. PY - 2011 DA - 2011// TI - Amyloid-beta interaction with mitochondria JO - Int. J. Alzheimers Dis. VL - 2011 ID - Pagani2011 ER - TY - JOUR AU - Mattson, M. P. AU - Chan, S. L. PY - 2001 DA - 2001// TI - Dysregulation of cellular calcium homeostasis in Alzheimer’s disease: Bad genes and bad habits JO - J. Mol. Neurosci. VL - 17 UR - https://doi.org/10.1385/JMN:17:2:205 DO - 10.1385/JMN:17:2:205 ID - Mattson2001 ER - TY - JOUR AU - Berridge, M. J. PY - 2014 DA - 2014// TI - Calcium regulation of neural rhythms, memory and Alzheimer’s disease JO - J. Physiol. VL - 592 UR - https://doi.org/10.1113/jphysiol.2013.257527 DO - 10.1113/jphysiol.2013.257527 ID - Berridge2014 ER - TY - JOUR AU - Cai, Z. AU - Zhao, B. AU - Ratka, A. PY - 2011 DA - 2011// TI - Oxidative stress and beta-amyloid protein in Alzheimer’s disease JO - Neuromolecular Med. VL - 13 UR - https://doi.org/10.1007/s12017-011-8155-9 DO - 10.1007/s12017-011-8155-9 ID - Cai2011 ER - TY - JOUR AU - Hynd, M. R. AU - Scott, H. L. AU - Dodd, P. R. PY - 2004 DA - 2004// TI - Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer’s disease JO - Neurochem. Int. VL - 45 UR - https://doi.org/10.1016/j.neuint.2004.03.007 DO - 10.1016/j.neuint.2004.03.007 ID - Hynd2004 ER - TY - JOUR AU - Kudo, W. PY - 2012 DA - 2012// TI - Inhibition of Bax protects neuronal cells from oligomeric Aβ neurotoxicity JO - Cell Death Dis. VL - 3 UR - https://doi.org/10.1038/cddis.2012.43 DO - 10.1038/cddis.2012.43 ID - Kudo2012 ER - TY - JOUR AU - Sanphui, P. AU - Biswas, S. C. PY - 2013 DA - 2013// TI - FoxO3a is activated and executes neuron death via Bim in response to beta-amyloid JO - Cell Death Dis. VL - 4 UR - https://doi.org/10.1038/cddis.2013.148 DO - 10.1038/cddis.2013.148 ID - Sanphui2013 ER - TY - JOUR AU - Townsend, M. AU - Mehta, T. AU - Selkoe, D. J. PY - 2007 DA - 2007// TI - Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway JO - J. Biol. Chem. VL - 282 UR - https://doi.org/10.1074/jbc.M610390200 DO - 10.1074/jbc.M610390200 ID - Townsend2007 ER - TY - JOUR AU - Magdesian, M. H. PY - 2008 DA - 2008// TI - Amyloid-beta binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt/beta-catenin signaling JO - J. Biol. Chem. VL - 283 UR - https://doi.org/10.1074/jbc.M707108200 DO - 10.1074/jbc.M707108200 ID - Magdesian2008 ER - TY - JOUR AU - Fryer, J. D. PY - 2005 DA - 2005// TI - Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model JO - J. Neurosci. VL - 25 UR - https://doi.org/10.1523/JNEUROSCI.5170-04.2005 DO - 10.1523/JNEUROSCI.5170-04.2005 ID - Fryer2005 ER - TY - JOUR AU - Vinters, H. V. PY - 1987 DA - 1987// TI - Cerebral amyloid angiopathy. A critical review JO - Stroke VL - 18 UR - https://doi.org/10.1161/01.STR.18.2.311 DO - 10.1161/01.STR.18.2.311 ID - Vinters1987 ER - TY - JOUR AU - Hsu, M. J. PY - 2007 DA - 2007// TI - Apoptosis signal-regulating kinase 1 in amyloid beta peptide-induced cerebral endothelial cell apoptosis JO - J. Neurosci. VL - 27 UR - https://doi.org/10.1523/JNEUROSCI.1874-06.2007 DO - 10.1523/JNEUROSCI.1874-06.2007 ID - Hsu2007 ER - TY - JOUR AU - Davis, J. AU - Cribbs, D. H. AU - Cotman, C. W. AU - Nostrand, W. E. PY - 1999 DA - 1999// TI - Pathogenic amyloid beta-protein induces apoptosis in cultured human cerebrovascular smooth muscle cells JO - Amyloid VL - 6 UR - https://doi.org/10.3109/13506129909007321 DO - 10.3109/13506129909007321 ID - Davis1999 ER - TY - JOUR AU - Torre, J. C. PY - 2004 DA - 2004// TI - Is Alzheimer’s disease a neurodegenerative or a vascular disorder? Data, dogma, and dialectics JO - Lancet Neurol. VL - 3 UR - https://doi.org/10.1016/S1474-4422(04)00683-0 DO - 10.1016/S1474-4422(04)00683-0 ID - Torre2004 ER - TY - JOUR AU - Hines, P. PY - 2013 DA - 2013// TI - Amyloid binding partners JO - Sci. Signal. VL - 6 ID - Hines2013 ER - TY - JOUR AU - Felice, F. G. PY - 2007 DA - 2007// TI - Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine JO - J. Biol. Chem. VL - 282 UR - https://doi.org/10.1074/jbc.M607483200 DO - 10.1074/jbc.M607483200 ID - Felice2007 ER - TY - JOUR AU - Wang, H. Y. PY - 2000 DA - 2000// TI - Beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer’s disease pathology JO - J. Biol. Chem. VL - 275 UR - https://doi.org/10.1074/jbc.275.8.5626 DO - 10.1074/jbc.275.8.5626 ID - Wang2000 ER - TY - JOUR AU - Coulson, E. J. PY - 2006 DA - 2006// TI - Does the p75 neurotrophin receptor mediate Aβ-induced toxicity in Alzheimer’s disease? JO - J. Neurochem. VL - 98 UR - https://doi.org/10.1111/j.1471-4159.2006.03905.x DO - 10.1111/j.1471-4159.2006.03905.x ID - Coulson2006 ER - TY - JOUR AU - Lauren, J. AU - Gimbel, D. A. AU - Nygaard, H. B. AU - Gilbert, J. W. AU - Strittmatter, S. M. PY - 2009 DA - 2009// TI - Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers JO - Nature VL - 457 UR - https://doi.org/10.1038/nature07761 DO - 10.1038/nature07761 ID - Lauren2009 ER - TY - JOUR AU - Sonkar, V. K. AU - Kulkarni, P. P. AU - Dash, D. PY - 2014 DA - 2014// TI - Amyloid beta peptide stimulates platelet activation through RhoA-dependent modulation of actomyosin organization JO - FASEB J. VL - 28 UR - https://doi.org/10.1096/fj.13-243691 DO - 10.1096/fj.13-243691 ID - Sonkar2014 ER - TY - JOUR AU - Ahn, H. J. PY - 2010 DA - 2010// TI - Alzheimer’s disease peptide beta-amyloid interacts with fibrinogen and induces its oligomerization JO - Proc. Natl. Acad. Sci. U. S. A. VL - 107 UR - https://doi.org/10.1073/pnas.1010373107 DO - 10.1073/pnas.1010373107 ID - Ahn2010 ER - TY - JOUR AU - Zamolodchikov, D. AU - Strickland, S. PY - 2012 DA - 2012// TI - Aβ delays fibrin clot lysis by altering fibrin structure and attenuating plasminogen binding to fibrin JO - Blood VL - 119 UR - https://doi.org/10.1182/blood-2011-11-389668 DO - 10.1182/blood-2011-11-389668 ID - Zamolodchikov2012 ER - TY - JOUR AU - Cortes-Canteli, M. PY - 2010 DA - 2010// TI - Fibrinogen and beta-amyloid association alters thrombosis and fibrinolysis: A possible contributing factor to Alzheimer’s disease JO - Neuron VL - 66 UR - https://doi.org/10.1016/j.neuron.2010.05.014 DO - 10.1016/j.neuron.2010.05.014 ID - Cortes-Canteli2010 ER - TY - JOUR AU - Ahn, H. J. PY - 2014 DA - 2014// TI - A novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer’s disease mice JO - J. Exp. Med. VL - 211 UR - https://doi.org/10.1084/jem.20131751 DO - 10.1084/jem.20131751 ID - Ahn2014 ER - TY - JOUR AU - Singh, S. K. PY - 2012 DA - 2012// TI - Amine-modified graphene: Thrombo-protective safer alternative to graphene oxide for biomedical applications JO - ACS Nano. VL - 6 UR - https://doi.org/10.1021/nn300172t DO - 10.1021/nn300172t ID - Singh2012 ER - TY - JOUR AU - Singh, S. K. PY - 2011 DA - 2011// TI - Thrombus inducing property of atomically thin graphene oxide sheets JO - ACS Nano. VL - 5 UR - https://doi.org/10.1021/nn201092p DO - 10.1021/nn201092p ID - Singh2011 ER - TY - JOUR AU - Grynkiewicz, G. AU - Poenie, M. AU - Tsien, R. Y. PY - 1985 DA - 1985// TI - A new generation of Ca2+ indicators with greatly improved fluorescence properties JO - J. Biol. Chem. VL - 260 ID - Grynkiewicz1985 ER - TY - JOUR AU - Soundararajan, R. PY - 2008 DA - 2008// TI - Quercetin 3-glucoside protects neuroblastoma (SH-SY5Y) cells in vitro against oxidative damage by inducing sterol regulatory element-binding protein-2-mediated cholesterol biosynthesis JO - J. Biol. Chem. VL - 283 UR - https://doi.org/10.1074/jbc.M703583200 DO - 10.1074/jbc.M703583200 ID - Soundararajan2008 ER - TY - JOUR AU - Shrivastava, S. PY - 2009 DA - 2009// TI - Characterization of antiplatelet properties of silver nanoparticles JO - ACS Nano. VL - 3 UR - https://doi.org/10.1021/nn900277t DO - 10.1021/nn900277t ID - Shrivastava2009 ER - TY - JOUR AU - Comeglio, P. PY - 1996 DA - 1996// TI - Blood clotting activation during normal pregnancy JO - Thromb. Res. VL - 84 UR - https://doi.org/10.1016/0049-3848(96)00176-4 DO - 10.1016/0049-3848(96)00176-4 ID - Comeglio1996 ER - TY - JOUR AU - Gowert, N. S. PY - 2014 DA - 2014// TI - Blood platelets in the progression of Alzheimer’s disease JO - PLoS One VL - 9 UR - https://doi.org/10.1371/journal.pone.0090523 DO - 10.1371/journal.pone.0090523 ID - Gowert2014 ER - TY - JOUR AU - Canobbio, I. PY - 2014 DA - 2014// TI - Amyloid beta-peptide-dependent activation of human platelets: Essential role for Ca2+ and ADP in aggregation and thrombus formation JO - Biochem. J. VL - 462 UR - https://doi.org/10.1042/BJ20140307 DO - 10.1042/BJ20140307 ID - Canobbio2014 ER - TY - JOUR AU - Nakagawa, K. PY - 2011 DA - 2011// TI - Amyloid beta-induced erythrocytic damage and its attenuation by carotenoids JO - FEBS Lett. VL - 585 UR - https://doi.org/10.1016/j.febslet.2011.03.060 DO - 10.1016/j.febslet.2011.03.060 ID - Nakagawa2011 ER - TY - JOUR AU - Hu, X. PY - 2009 DA - 2009// TI - Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide JO - Proc. Natl. Acad. Sci. U. S. A. VL - 106 UR - https://doi.org/10.1073/pnas.0911281106 DO - 10.1073/pnas.0911281106 ID - Hu2009 ER - TY - JOUR AU - Behl, C. AU - Davis, J. B. AU - Lesley, R. AU - Schubert, D. PY - 1994 DA - 1994// TI - Hydrogen peroxide mediates amyloid beta protein toxicity JO - Cell VL - 77 UR - https://doi.org/10.1016/0092-8674(94)90131-7 DO - 10.1016/0092-8674(94)90131-7 ID - Behl1994 ER - TY - JOUR AU - Sagara, Y. AU - Dargusch, R. AU - Klier, F. G. AU - Schubert, D. AU - Behl, C. PY - 1996 DA - 1996// TI - Increased antioxidant enzyme activity in amyloid beta protein-resistant cells JO - J. Neurosci. VL - 16 UR - https://doi.org/10.1523/JNEUROSCI.16-02-00497.1996 DO - 10.1523/JNEUROSCI.16-02-00497.1996 ID - Sagara1996 ER - TY - JOUR AU - Jarre, A. PY - 2014 DA - 2014// TI - Pre-activated blood platelets and a pro-thrombotic phenotype in APP23 mice modeling Alzheimer’s disease JO - Cell. Signal. VL - 26 UR - https://doi.org/10.1016/j.cellsig.2014.05.019 DO - 10.1016/j.cellsig.2014.05.019 ID - Jarre2014 ER - TY - JOUR AU - Bush, A. I. PY - 1990 DA - 1990// TI - The amyloid precursor protein of Alzheimer’s disease is released by human platelets JO - J. Biol. Chem. VL - 265 ID - Bush1990 ER - TY - JOUR AU - Vassar, R. PY - 1999 DA - 1999// TI - Beta-secretase cleavage of Alzheimer’s amyloid precursor protein by the transmembrane aspartic protease BACE JO - Science VL - 286 UR - https://doi.org/10.1126/science.286.5440.735 DO - 10.1126/science.286.5440.735 ID - Vassar1999 ER - TY - JOUR AU - Skovronsky, D. M. AU - Lee, V. M. AU - Pratico, D. PY - 2001 DA - 2001// TI - Amyloid precursor protein and amyloid beta peptide in human platelets. Role of cyclooxygenase and protein kinase C JO - J. Biol. Chem. VL - 276 UR - https://doi.org/10.1074/jbc.M006285200 DO - 10.1074/jbc.M006285200 ID - Skovronsky2001 ER - TY - JOUR AU - Smith, C. C. PY - 1997 DA - 1997// TI - Stimulated release of the beta-amyloid protein of Alzheimer’s disease by normal human platelets JO - Neurosci. Lett. VL - 235 UR - https://doi.org/10.1016/S0304-3940(97)00738-6 DO - 10.1016/S0304-3940(97)00738-6 ID - Smith1997 ER - TY - JOUR AU - Deane, R. AU - Wu, Z. AU - Zlokovic, B. V. PY - 2004 DA - 2004// TI - RAGE (yin) versus LRP (yang) balance regulates alzheimer amyloid beta-peptide clearance through transport across the blood-brain barrier JO - Stroke VL - 35 UR - https://doi.org/10.1161/01.STR.0000143452.85382.d1 DO - 10.1161/01.STR.0000143452.85382.d1 ID - Deane2004 ER - TY - JOUR AU - Roher, A. E. PY - 2009 DA - 2009// TI - Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer’s disease JO - Alzheimers Dement. VL - 5 UR - https://doi.org/10.1016/j.jalz.2008.10.004 DO - 10.1016/j.jalz.2008.10.004 ID - Roher2009 ER - TY - JOUR AU - Canobbio, I. PY - 2013 DA - 2013// TI - Immobilized amyloid Aβ peptides support platelet adhesion and activation JO - FEBS Lett. VL - 587 UR - https://doi.org/10.1016/j.febslet.2013.06.041 DO - 10.1016/j.febslet.2013.06.041 ID - Canobbio2013 ER - TY - JOUR AU - Ryu, J. K. AU - McLarnon, J. G. PY - 2009 DA - 2009// TI - A leaky blood-brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer’s disease brain JO - J. Cell. Mol. Med. VL - 13 UR - https://doi.org/10.1111/j.1582-4934.2008.00434.x DO - 10.1111/j.1582-4934.2008.00434.x ID - Ryu2009 ER - TY - JOUR AU - Sagare, A. P. AU - Bell, R. D. AU - Zlokovic, B. V. PY - 2013 DA - 2013// TI - Neuro-ascular defects and faulty amyloid-β vascular clearance in Alzheimer’s disease JO - J. Alzheimers Dis. VL - 33 ID - Sagare2013 ER - TY - JOUR AU - Cortes-Canteli, M. a. r. t. a. AU - Mattei, L. a. r. i. s. s. a. AU - Richards, A. l. l. i. s. o. n. T. AU - Norris, E. r. i. n. H. AU - Strickland, S. i. d. n. e. y. PY - 2015 DA - 2015// TI - Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration JO - Neurobiology of Aging VL - 36 UR - https://doi.org/10.1016/j.neurobiolaging.2014.10.030 DO - 10.1016/j.neurobiolaging.2014.10.030 ID - Cortes-Canteli2015 ER -