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Figure 2 | Molecular Medicine

Figure 2

From: Plasma Fibrinogen Is a Natural Deterrent to Amyloid β-Induced Platelet Activation and Neuronal Toxicity

Figure 2

(A) Aβ25–35 induced rise in intracellular ROS in the absence and presence of fibrinogen (2 mg/mL) as indicated. (B) Aβ25_35 induced rise in intracellular calcium in the absence and presence of fibrinogen (2 mg/mL) as indicated. (C) Immunoblots representing MYPT1 phosphorylation in washed platelets stimulated with Aβ40 (20 µmol/L for 5 min) in the presence or absence of fibrinogen (3 mg/mL). (D) Corresponding bar diagram representing the densitometric analyses of immunoblots for p-MYPT1. *p < 0.05 with respect to control platelets; #p < 0.05 with respect to Aβ40-treated platelets.

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