Figure 3

Interaction of fluorescently labeled Aβ with platelets. (A) Washed platelets labeled with CD41a-FITC (WPCD41a); (B) washed platelets treated with Hylite-555-labeled Aβ₄₂ (Aβ-FL); (C) CD41a-FITC-labeled washed platelets incubated with fluorescently labeled Aβ₄₂ (Aβ-FL); (D) CD41a-FITC-labeled washed platelets preincubated with fibrinogen (Fg; 2 mg/mL) followed by treatment with fluorescently labeled Aβ₄₂ (Aβ-FL); (E) CD41a-FITC-labeled washed platelets preincubated with BSA (2 mg/mL) followed by treatment with fluorescently labeled Aβ₄₂ (Aβ-FL); (F) CD41a-FITC-labeled platelets suspended in plasma (PRPCD41a) treated with fluorescently labeled Aβ₄₂ (Aβ-FL).