Intracellular localization of Aβ42 in neuronal cells. (A) SH-SY5Y cells labeled with Hylite-555-Aβ42 pretreated with saline (upper panel), fibrinogen (middle panel) or BSA (lower panel). Arrows indicate localization of Aβ42 (red) inside cells. (B) The bars represent the number of SH-SY5Y cells positive and negative for Aβ42. Data are representative of about 250 cells counted in 10 low-power (10×) fields. #p < 0.05 with respect to Aβ42-treated cells in the absence of fibrinogen.