Figure 1
Screening and selection of a short list of potential new targets. Diagram bounding several stages to identify common genes in cardiovascular disease and obesity models. Differentially expressed genes from cardiovascular disease meta-analysis and type 2 diabetes and adipose tissue microarrays were combined to identify common genes upregulated in all 3 studies. First, common genes from all 3 databases were identified (22 genes) to proceed with identification of the upregulated genes in 3 out of 3 studies (8 genes). The aorta microarray was not included in the selection procedure, as no differentially expressed genes were found after Benjamini-Hochberg correction.