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Figure 1 | Molecular Medicine

Figure 1

From: Tolerogenic Dendritic Cells Induced by BD750 Ameliorate Proinflammatory T cell Responses and Experimental Autoimmune Encephalitis in Mice

Figure 1

Morphological characteristics and survival of typical mDCs and BD750-treated DCs. BMDCs were stimulated with cytokines and treated with or without BD750 at the indicated dose or CP690550 for 12 h and then further stimulated with LPS for 24 h. The imDCs, mDCs and BD750-treated DCs were observed by a light microscope, and the percentages of apoptotic DCs in different groups of cells were determined by flow cytometry analysis. Data are representative images or expressed as the mean ± SEM of three independent experiments. (A) Light microscopic analysis of different groups of DCs. (B) Flow cytometry analysis of apoptotic cells. (C) Quantitative analysis of apoptotic cells. *P < 0.05, **P < 0.01 versus the mDC group.

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Molecular Medicine

ISSN: 1528-3658