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Figure 4 | Molecular Medicine

Figure 4

From: Tolerogenic Dendritic Cells Induced by BD750 Ameliorate Proinflammatory T cell Responses and Experimental Autoimmune Encephalitis in Mice

Figure 4

BD750-treated DC impairs allogeneic antigen-stimulated T cell proliferation in vitro. ImDCs, mDCs and BD750-pretreated DCs (12 h) were mixed in triplicate with carboxyfluo-resceinsuccinimidyl ester-labeled allogeneic naive CD4+CD25− T cells for 72 h at different ratios (DC:CD4 + T, 1:10, 1:30 and 1:100), and the proliferation of T cells was determined by flow cytometry. Data are representative histograms or expressed as the mean ± SEM of three independent experiments. (A) Flow cytometry analysis. (B-D) Quantitative analysis. *P < 0.05, **P < 0.01 versus the mDC group.

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