miR-155 deficiency is associated with decreased expression of granzyme A (a marker of cytotoxic T lymphocytes and natural killer cells) and heme oxygenase-1 (a marker of oxidative stress) in response to P. berghei ANKA (PbA)-induced ECM. Median brain mRNA levels in albino C57BL/6 miR-155−/− versus wild-type miR-155+/+ littermate controls on d 6 post-PbA infection (1 × 106 parasitized erythrocytes), measured by qRT-PCR. Gzma and Ho-1 mRNA were significantly decreased in miR-155−/− versus wildtype PbA-infected mice (*P < 0.05; Mann-Whitney test; n = 7/group). Experiment was repeated for confirmation of findings. Error bars represent interquartile range. Abbreviations: Gzma, granzyme A; Ho-1, heme oxygenase-1.