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Figure 7 | Molecular Medicine

Figure 7

From: α-1 Antitrypsin Inhibits RANKL-induced Osteoclast Formation and Functions

Figure 7

AAT inhibits CatK activity and gene expression. (A) Percentage of inhibition of CatK activity by AAT determined by CatK drug discovery kit. b Effect of AAT treatment (2 mg/mL) on CatK gene expression (fold changes of CatK mRNA expression) was determined by qPCR. Values are means ± SEM of at least triplicate samples. Data were analyzed using one-way analysis of variance followed by Dunnett’s multiple comparison test. ***p <0.0001.

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