Figure 3
From: Data-Driven Modeling for Precision Medicine in Pediatric Acute Liver Failure
Significant circulating inflammatory mediators and connections in PALF patients (DyNA, high stringency). Circulating inflammatory mediators in serum samples from PALF patients were measured and DyNA (stringency level = 0.95) was performed during seven time frames, d 0–1, d 1–2, d 2–3, d 3–4, d 4–5, d 5–6, d 6–7, as described in Materials and Methods. Results show the significant mediators based on dynamic patterns and network connectivity in three main groups of PALF patients (panel A: nonsurvivors, n = 12; panel B: LTx recipients, n = 28; and panel C: spontaneous survivors, n = 61).